About BRL

U.S.-based Biomedical Research Laboratories (BRL) was founded in 2008 by a team of bioengineers from the University of California. BRL has a fundamentally different approach to the development of nutritional supplements that involves peer-reviewed research and clinical studies. Our company is dedicated to improving the lives of our customers through science and nutrition. The company’s natural remedy products, Prohemia®, Altitude-Rx®, and CalmLegs®, provide lasting relief from serious medical conditions without the risk of side effects.

About Calm Legs

We had friends and family members who suffered from Restless Leg Syndrome and discovered the pharmaceutical approach was not working for them. There were just too many side effects, addictive pain medications and many of the drugs used to treat caused a worsening of their condition. We looked at the latest research and formulated Calm Legs based on ingredients that were shown in clinical trials to have effects in combating the symptoms of RLS. The combination of ingredients in Calm Legs relieved their symptoms and allowed them to sleep restfully symptom free for the first time in years.

Commitment to Research

Research is a top priority at Biomedical Research Laboratories. We are driven by a desire to ensure our products are proven to work and have scientific validation. We refuse to reduce costs by using small amounts of ingredients just to dress up the label. Our formulations utilize the same levels of the active ingredients that were used in the actual human studies. We are meticulous about research and go out of our way to make sure we have addressed each of our stringent requirements. All products that BRL develops are based on peer-reviewed scientific research.

Commitment to Quality, Purity and Safety

Every ingredient in Calm Legs has been thoroughly researched and tested to ensure its safety, efficacy and potency. We use the latest technology and production capabilities available only at our FDA-registered production facility in the United States. We have uncompromising high standards and only use the highest quality ingredients. We employ the latest technological advancements in the production of all of our products.


The FDA’s official standards of current Good Manufacturing Practices (cGMP) are upheld in all of our operations and our facility has received independent cGMP verification.

Our Mission

To develop natural formulations that are scientifically validated through clinical research and to maintain a strong commitment to quality and continue to find solutions to improve the natural supplements available to unique populations.