Crohns and Restless Legs (RLS) Study
by Bradley Gillespie, PharmD Health Expert, Restless Leg Sufferer
Leonard Weinstock, MD, of Washington University School of Medicine, in St. Louis, Missouri, and colleagues, noted that manifestations of Crohn’s Disease affecting the central nervous system have not previously been reported in the scientific literature.
Since Restless Legs (RLS) can be caused by so many different factors, Weinstock, et al, conducted an investigation to determine if Restless Legs (RLS) was associated with Crohn’s Disease. Their hypothesis was that there may be a relationship, because both disorders are associated with iron deficiency, inflammation and bacterial infections.
In this study, the investigators enrolled a total of 272 Crohn’s Disease patients with an average age of 47 years. Of these patients, 78% had involvement of their small intestine, and 40% suffered colon involvement. All subjects were surveyed for the presence and prevalence of Restless Legs (RLS). Additionally, information on individual clinical characteristics, risk factors and a quantitative relationship between the two disorders was assessed.
The outcome of the study was remarkable, with an incidence of Restless Legs (RLS) in Crohn’s Disease patients approaching 43%.
Additionally, in 92% of patients with Restless Legs (RLS), these symptoms began during or after the diagnosis of Crohn’s Disease. Of the 73 patients with Restless Legs (RLS), 45% noted that there was a relationship between improvements in their symptoms of Crohn’s Disease and their symptoms of Restless Legs (RLS).
This work clearly demonstrates that Restless Legs (RLS) is a frequent disorder occurring in people who also suffer from Crohn’s Disease, and that Restless Legs (RLS) may be caused by a factor outside of the gastrointestinal system, although Crohn’s Disease is clearly a gastrointestinal disease (Inflammatory Bowel Diseases. Volume 16, Issue 2, pages 275–279, February 2010).
So, as in other gastrointestinal diseases, such as Celiac Disease, it appears likely that these patients are highly susceptible to also being afflicted with Restless Legs (RLS). The patients have enough to worry about without dealing with the additional problems associated with Restless Legs (RLS). As such, it is advisable that patients with Crohn’s Disease also be evaluated for Restless Legs (RLS), and if needed, treated to relieve their symptoms.
The patent pending CalmLegs™ may be an ideal natural remedy approach to alleviating the symptom’s of Restless Legs (RLS).
“Nights were horrible for me, endless pain, legs jerking, lost sleep, drowsy days, worried about driving, my husbands lack of sleep. Life was hell before trying your product. After taking Calm Legs for a couple of weeks, I fell asleep peacefully for the first time in years.”