Marcello Moccia, MS, of the Department of Neurological Sciences at the University Federico II and IDC Hermitage Capodimonte in Naples, Italy, and colleagues, set out to investigate the relationship between Restless Legs (RLS) and celiac disease (CD). The basis of their investigation was that iron-related anemia, due to mal-absorption, is common in CD, and such iron deficiencies are also often found in restless leg patients.
Restless Legs (RLS) and Celiac Disease Study
In order to complete their investigation, they screened a population of 100 adults stricken with celiac disease for features such as iron metabolism, neurological and clinical conditions. In addition, to provide proper balance, they also included 100 age and sex-matched general population, control subjects in the study.
The presence of restless leg was determined in all subjects by characterizing four essential diagnostic criteria recognized by the international restless leg Study Group. Based on these parameters, a restless leg Study Group rating scale was used to measure the severity of restless leg.
31% with Restless Legs (RLS) and Celiac Disease
The investigators found that restless leg was present in 31% of celiac disease patients, while only 4% of the control population were afflicted. The average severity of restless leg in the celiac disease population was moderate. There was no significant relationship found between the presence of restless leg and either a gluten-free diet, or iron metabolism, despite the fact that hemoglobin levels were significantly lower in celiac disease patients with restless leg, than in patients that did not suffer restless leg.
The investigators concluded that patients with celiac disease have a higher incidence of restless leg than the general population (Movement Disorders. Volume 25, Issue 7, pages 877–881, 15 May 2010).
This research suggests that patients with celiac disease are much more likely to be afflicted with restless leg than other patients. As a result, patients with celiac disease should be evaluated carefully forrestless leg.
If patients, indeed, do have restless leg, Calm Leg™ Restless Leg Remedy should be considered as a good addition to their overall treatment regimen. Calm Legs® is gluten free.
Bradley Gillespie, PharmD
Health Expert, Restless Leg Sufferer
“I get a creepy-crawly feeling in my legs that makes me want to get up and move constantly, after 3 weeks of using Calm Legs I can finally relax and my life is so much better”