Restless Legs and Type 2 Diabetes

Giovanni Merlino, MD at the University of Udine, in Italy, and his colleagues, set out to investigate the relationship between Restless Legs (RLS) and Type 2 diabetes. In this work, they carefully examined the characteristics of Restless Legs (RLS)  in diabetics, as well as the potential Restless Legs (RLS)  risk factors specific to diabetics.

Diabetes and Restless Legs (RLS)While it is known that Restless Legs (RLS) may be the result of a number of other conditions, such as diabetes, neuropathy, kidney disease, central nervous system trauma or iron deficiency, this may be the first systematic examination of the relationship between diabetes and Restless Legs (RLS) .

Dr. Merlino and his collaborators studied a total of 124 diabetic patients at their university diabetic outpatient treatment center, as well as 87 control subjects (people without diabetes). Interestingly, Restless Legs (RLS)  was diagnosed in approximately 18% of the diabetics, and in only 5.5% of the controls. Statistical analyses, showed an inter-relationship between the maladies, resulting in their conclusion that Restless Legs (RLS) is highly prevalent in type 2 diabetic patients.

In order to try and determine the cause of Restless Legs (RLS)  in diabetics, they also examined patients for the presence of polyneuropathy, a generalized disorder of the peripheral nerves that is commonly found in diabetics. While there was a modest relationship, the presence of polyneuropathy was not able to fully explain the relationship.

Chronic sleep deprivation, often found in patients suffering from Restless Legs (RLS), has been positively linked to an increased risk of cardiovascular disease and its related mortality. This documented linkage, as well as an associated increase in the incidence of high blood pressure, may provide an explanation for the increased risk of cardiovascular disease in patients with Restless Legs (RLS).

While Dr. Merlino stressed the importance of treating Restless Legs (RLS) to manage the cardiovascular risks associated with diabetes, he also noted that the literature describes cases of Restless Legs (RLS) itself as a causative factor in type 2 diabetes (Sleep. 2007; 30:866-871).

The serious nature of the information presented in this posting, reinforces the need to effectively manage the symptoms of Restless Legs (RLS) . The fine-tuned list of ingredients used in the making of CalmLegs®, make it an effective treatment choice.

Bradley Gillespie, PharmD

Health Expert
Restless Leg Sufferer